Marijuana Dispensaries in Independence, Missouri

This directory lists 11 licensed marijuana dispensaries in Independence, MI. Marijuana — also called cannabis or weed — is legal for adults 21 and older in Independence and throughout Missouri.

Every Independence marijuana dispensary listed here is licensed by the Missouri Division of Cannabis Regulation (DCR). Browse below for store locations, hours, contact details, and product menus.

Marijuana Dispensaries in Independence, Missouri — Listings

  • NatureMed Dispensary

    Licensed cannabis dispensary in 15823 E US Hwy 24, Independence, MO 64050.

    15823 E US Hwy 24, Independence, MO 64050

  • Sacred Leaf

    Licensed cannabis dispensary in 2314 S Lee's Summit Rd, Independence, MO 64055.

    2314 S Lee's Summit Rd, Independence, MO 64055

  • Herb Depot Dispensary

    Licensed cannabis dispensary in 12500 E US Hwy 40 J, Independence, MO 64055.

    12500 E US Hwy 40 J, Independence, MO 64055

  • TCB Cannabis Collections Co.

    Licensed cannabis dispensary in 15803 East 23rd St S, Independence, MO 64055.

    15803 East 23rd St S, Independence, MO 64055

  • Green Gene CBD

    Licensed cannabis dispensary in 18801 East 39th St S Ste 2046, Independence, MO 64057.

    18801 East 39th St S Ste 2046, Independence, MO 64057

  • Gray Area

    Licensed cannabis dispensary in 20001 E Jackson Dr, Independence, MO 64057.

    20001 E Jackson Dr, Independence, MO 64057

Frequently Asked Questions

Is marijuana legal in Independence, Missouri?

Yes. Adult-use recreational marijuana is legal throughout Missouri, including Independence, for adults 21 and older under Amendment 3 (2022). Every dispensary must hold a valid license from the Missouri Division of Cannabis Regulation (DCR).

Do I need a medical card to buy marijuana in Independence?

No. Adults 21 and older can buy recreational marijuana at licensed dispensaries in Independence without a medical card. A valid government-issued photo ID is required at purchase.

What is the difference between marijuana and cannabis dispensaries in Independence?

There is no difference — "marijuana," "weed," and "cannabis" all refer to the same product. Missouri's licensed dispensaries in Independence sell adult-use recreational marijuana to anyone 21 and older.

What marijuana products can I buy in Independence?

Licensed dispensaries in Independence, Missouri carry a regulated range of marijuana products including flower, pre-rolls, edibles, gummies, vape cartridges, concentrates, tinctures, and topicals — all third-party lab tested under Missouri state law.

What time do dispensaries open in Independence, Missouri?

Dispensary hours in Independence vary by location. Many open around 9–10 a.m. and close around 8–9 p.m., with some open later. Check each Independence listing below for current hours and call ahead to confirm.